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The difference in the frequency of risk factors and in-hospital mortality among hypertensive and normotensive patients with acute myocardial infarction in durres population

Author: 
Eliverta Zera, Prof. Ass Elizana Zaimi Petrela and Prof. Dr Mimoza Lezha
Subject Area: 
Health Sciences
Abstract: 

Background: The patients suffering from hypertension demonstrate a higher risk development of CHD. Arterial hypertension (AH) is one of the main factors to cardiovascular diseases (CVD) and general mortality. Aim: The objective of this study was to determine the difference in the frequency of risk factors and in-hospital outcome in hypertensive and normotensive patients with AMI in Durres population, Albania. Methods: The study included 454 patients with acute myocardial infarction (AMI) admitted to in the Cardiology Department, Regional Hospital of Durres, Albania between January 2009 to October 2012 . In hypertensive and normotensive patients with AMI were analysed risk factors (cigarette smoking, age, gender, hypertension and blood lipids, diabetes, obesity, family history, previous MI,AMI localization) Results: Of 454 pts ,327(72.03%) were male and 127 (27.97%) were women. 264 (58.1%) patients were hypertensive. Comparing to men,women presented less frequently with hypertension (64.39% vs 35.61% to women respectively). Hypertensive pts were younger than normotensive pts (61.93±11.21 vs 64.81±10.85, p 0.005). We did not find significant differences in age among females or males in both groups (hypertensive vs normotensive). According to the age group a statistically significant difference was recorded only in the age group from 45-54 years. (12.1%vs 21.1% in normotensive (p 0.008). Hypertensive patients had obesity (p=0.017; RR:1.59; CI95%: 1.093-2.325) and dislipidemia (p<0.001, RR:4.04; CI95%: 2.651-6,161). Normotensive patients had smoking habits (p=0.002) and family history (p=0.021), No significant differences were found between hypertensive and normotensive patients with regard to other risk factors. In-hospital mortality was higher in hypertensive patients.13(4.9%) out of 14(3.1%) patients with fatal MI were hypertensive.(p=0.005, OD: 5.73;CI95%: 1.263-7.088). Conclusion: In hospital mortality was higher in hypertensive as compared to normotensive patients with AMI. Hypertensive patients were younger than normotensive patients. No significant differences were found between hypertensive and normotensive patients with regard to other risk factor. Women were older than men in both groups. It is not sufficient to analyze risk factors of patients with AMI stratified by hypertension status to accurately predict the early outcome.

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