A double blind study comparing the efficacy of ibuprofen, diclofenac sodium and placebo after periodontal surgery

Background: This study examined the efficacy of Ibuprofen, Diclofenac sodium and Placebo on the intensity of pain relief and on the gingival crevicular fluid levels before and after periodontal surgery. Methods: A double blind study was conducted on 25 male patients. Pain intensity and, GCF levels were assessed by Cooper and Beaver’s criteria and Mann’s method respectively. Statistical analysis was done by Kruskall Wallis and Friedmans test and p values were obtained. Results: Post operative mean pain intensity scores were significant (p value<0.01). Mean pre and post operative GCF levels were statistically significant at 1%. Conclusion: Patients who had Diclofenac sodium showed greater analgesic effect when compared to Ibuprofen and placebo. Similar reduction in the levels of GCF were observed with Ibuprofen and Diclofenac sodium than placebo.