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Effect of ginkgo biloba extracts and ginkgo biloba gold nanoparticles on 1-methyl-4-phenyl-1,2,3,6-tetra hydro pyridine induced behavioral deficits in mice model of parkinson's disease

Author: 
Thavaprakasam Arundoss, Subramanian Arulkumar, Karumbayiram Senthil Kumar and Krishnamoorthy Vasudevan
Subject Area: 
Life Sciences
Abstract: 

The present study aimed to evaluate the effect of Ginkgo biloba extract (GBE) and Ginkgo biloba gold nano particles (GBGNPs) on MPTP induced behavioral change in Parkinson’s disease mouse, investigated through the following behavioral test such as rotarod performance hang test, narrow beam walking, akinesia and catalepsy. The results indicate a significant variation in behavioral patterns of control and experiment groups. G.biloba may be useful for the management of neuropathic pain. When compare to GBE the GBGNPs showed better improvement in all behaviour tests.

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