This paper discusses the effect of total quality management on the management of the Cross River University of Technology (CRUTECH) and concludes that total quality management is consistent with higher education environment and is based on fundamental educational values such as human resource development, life-long learning, rational problem solving and social benefit. These higher education quality principles emphasize the fact that the information students get in the classrooms should be reinforced in the manner CRUTECH is being operated. They should be a conceptual shift from person-focused to system-focused thinking. It is essential that total quality management should be the basis of how work is performed, the quality of students trained in the University, how people are held accountable for what they do in the institutions, how people are evaluated, promoted or disciplined and how effectively higher education services are provided. This should be the hallmark of applying total quality management to the management of not only CRUTRECH but also other universities in Nigeria.