Background: Motivation is an internal driving force to create the circumstances that influence students to do work hard. Besides, memory is an ability to recall past events or previously learnt information and utilize the skills for practical purpose. Objectives: The objectives of the present study were to assess the effects of yoga module on global motivation and memory in relation to perceived stress of medical students. Design: Pre - post design was used to measure the effects the module. 120 female students who had 60 low stress and 60 high stress on the stress scale (PSS) and were selected and randomly assigned into experimental and control groups. The experimental group was exposed to yoga module- consisting of yoga asanas, for 12 weeks covering a total of 40 sessions. The control group was not exposed to the training for the entire period. Materials: The global motivation scale (GMS) Frédéric Guay, Geneviève A. Mageauet Robert J. Valler and 29:8, 2003, and (PGI) memory scale by Pershad, Dwarka and N.N Wing were used to the groups at before and after assessments.