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Efficacy of occimum sanctum (tulsi) and oral antioxidants (sm fibro) in the management of oral submucous fibrosis: a randomized clinical trial

Author: 
Dr. Sunita Kulkarni, Dr. Usha Rathod, Dr. Vaishali Agrawal and Dr. Rucha Pandhripande
Subject Area: 
Health Sciences
Abstract: 

Introduction: Oral submucous fibrosis (OSMF) is one of the most prevalent premalignant conditions in India and difficult to treat. Recently many plants and fruit extract has been used. Tulsi (Occimum sanctum Linn) ‘basil’ is one such plant with many medicinal values. Although the disease is advancing rapidly, its reliable treatment modality for its various stages has not yet evolved. So the aim of the study is to evaluate the efficacy of tulsi and oral antioxidants (SM FIBRO) in the treatment of OSMF. Aim: To evaluates the efficacy of tulsi and oral antioxidants (SM FIBRO) in the treatment of OSMF. Materials and method- A randomized clinical trial of 100 OSMF patients were carried out in the department of oral medicine and radiology to evaluate the efficacy of occimum sanctum (TULSI) and oral antioxidants (SM FIBRO) in the management of oral submucous fibrosis. Result: The result of study showed statistically significant improvement in mouth opening, burning sensation, cheek flexibility and tongue protrusion in tulsi plus antioxidant group. Conclusion: Tulsi and oral antioxidant combination is safe and promising treatment modality for oral submucous fibrosis.

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