CALL FOR PAPERS

Author Information

CERTIFICATE

IMPACT FACTOR 2019

Subject Area

Life Sciences / Biology
Architecture / Building Management
Asian Studies
Business & Management
Chemistry
Computer Science
Economics & Finance
Engineering / Acoustics
Environmental Science
Agricultural Sciences
Pharmaceutical Sciences
General Sciences
Materials Science
Mathematics
Medicine
Nanotechnology & Nanoscience
Nonlinear Science
Chaos & Dynamical Systems
Physics
Social Sciences & Humanities

Why Us? >>

Open Access
Peer Reviewed
Rapid Publication
Life time hosting
Free promotion service
Free indexing service
More citations
Search engine friendly

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

An Efficient Reduction Process At Key Intermediate Stages In Dabigatran, Domperidone And Olanzapine Api’s

Author:

Shiva Rama Krishna Samala, Srishylam, V., Kranthi Kumar, T., Sreenivasulu, R. and Devanna

Subject Area:

Life Sciences

Abstract:

Objective: The present paper describes the simple and efficient protocol for the reduction of key intermediates in three API’s like Dabigatran, Domperidone and Olanzapine using Iron metal with Ammonium formate as main reagents with suitable solvent system. In Dabigatran and Domperidone the conversions are nitro to amine and in Olanzapine nitrile reduction followed by cyclization.

PDF file: