
The relationship between periodontal and endodontic disease has aroused confusion, queries and controversy. Differential diagnosis has always been difficult for periodontal and endodontic diseases. A symptomatic tooth may have pain of periodontal or pulpal origin. The nature of pain for that symptomatic tooth helps in determining the etiology of such a problem. Radiographic and clinical diagnosis helps in clarifying the nature of the problem. In some cases, the influence of pulpal pathology may create periodontal involvement. In others, periodontal pathology may create pulpal pathology. This review article discusses the various clinical aspects to be considered for correct diagnosis and treatment.