Erythroderma : study of clinico- etiology and complications from Western India

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Author: 
Dr. Mithali Jage and Dr. Sunanda Mahajan
Subject Area: 
Health Sciences
Abstract: 

Background : Erythroderma is extreme state of skin irritation involving more than 90 percent of skin surface area having many underlying causes. Aim: 1. To check for epidemiological factors in erythroderma. 2.To study clinical features of erythroderma. 3. To identify the aetiology of erythroderma. 4. To describe the complications of erythroderma Materials and Methods: This study was performed at the department of dermatology in a tertiary care hospital of Western India. We studied 31 cases of erythroderma for epidemiology, clinical features, clinical course and complications. Clinico-pathological correlation was done for aetiology of erythroderma. Statistical method used : student t test unpaired and chi square test Results: The mean age of onset was 43.99 years with a male to female ratio of 2.1:1. The clinical features found were redness, scaling, pruritus, fever, chills, lymphadenopathy and edema. On clinicopathological correlation the most common aetiology found was psoriasis vulgaris, (35.48%). This was followed by drug (included both drug induced erythroderma and DRESS syndrome) (22.5%). Remaining cases belonged to dermatitis (16.12%) (Contact dermatitis (two), photoallergic dermatitis (three)), and 6.45% (n=2) patients belonged to each of pemphigus foliaceus, NBIE, paraneoplastic dermatomyositis and generalised pustular psoriasis. Complications like hypoproteinemia (45.16%), electrolyte imbalance (45.16%), temperature dysregulation (22.5%) and secondary infection (32.25%) were observed. Limitations : Follow up of cases was not studied to know the long term sequel. Conclusion: Clinical features were identical irrespective of aetiology. Detailed clinic-pathological examination helps to establish the aetiology of erythroderma. Monitoring of vitals and biochemical parameters is essential for early diagnosis of complications and its management.

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Editorial Board Member's

Dr.Geetanjali Joshi Mishra
Lucknow, UP, INDIA
Dr. Sankalp Verma
India
Tannu Arora
India
Prof Dr. Lee Mun Seng
Malaysia
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
Dr. Lim Gee Nee
Malaysia
DANA MOHAMMED
UK
Ali Majnoony Tootakhaneh
Iran
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Thailand
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Turkey
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Pakistan
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Iran
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Uzbekistan
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Jordan
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Saudi Arabia
Eric Randy Reyes Politud
Philippines
Eapen, Asha Sarah
USA
Dr. Ruchika Khanna
India
DR. MUHAMMAD ISMAIL MOHMAND
UK
DR. MAHESH SHIVAJI CHAVAN
India
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India
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Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
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India
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Indonesia
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Algeria
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