Hyperlipidemia is a condition where there is an elevation of serum levels of total cholesterol(TC) and triglycerides(TGL) due to the lipid metabolism alteration, with an increase in the liver lipogenesis and lipolysis in the adipocytes. It is well known that a causal relationship exists between serum lipid levels and systemic health particularly cardiovascular diseases, diabetes and tissue repair capacity. It is hypothesized thatperiodontitis causes bacteremia or endotoxemia producing a cytokine cascade that leads to increase levels of pro-inflammatory cytokines which results in fat metabolism and hyperlipidemia. On the other hand psychological stress can down regulate the cellular immune response. Stress disrupts the homeostasis, which inturn alters the immune function. The association of stress with periodontal disease is said to be a risk factor. This study is conducted to evaluate the association between the stress levels and the lipid profile in patients with periodontitis.
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