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Evaluation of hexane crude extracts (root, stem, leaf and fruit body) of abutilon theophrasti medik for anti fungal activity

Author: 
Musheerul Hassan, Dr. Huma Habib and Dr. Reyaz Ahmad Mir
Subject Area: 
Life Sciences
Abstract: 

The investigation was aimed to carry out the antifungal activities of the hexane extract’s of Abutilon theophrasti against four fungal species, (Microsporum gypseum, Penicillium spp, Fusarium spp, Aspergillus spp). Disc-diffusion method was employed to carry out the antifungal activity against selected fungal species. Three concentrations (100µg/ml, 250 µg/ml, 500 µg/ml) were made to check the activity of crude extracts. Itraconazole was taken as standard reference drug, While as dimethyl sulphoxide (DMSO) served as negative control. Leaf extracts were found to show promising activity, followed by extracts of fruit body, stem and root. All crude extracts displayed their maximum inhibition against Fusarium species. Maximum inhibition (ZOI-11) was seen in crude extracts of leaves, followed by crude extracts of fruit body with inhibition zone of 10mm. Stem extracts displayed inhibition zone of 9mm while as root showed activity of 7mm. All inhibition activity was concentration dependent.

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