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Exuberant response to late onset of recombinant human growth hormone (rhgh) in patient with pan-hypopituitarism: Case Report

Author: 
Luilson Geraldo Coelho Júnior, Rafaela Araújo Guizetti, Alessandra de Paiva Wanderley, Thales Carvalho Araújo, Débora Gonçalves da Silva and Daniela de Stefani Marquez
Subject Area: 
Health Sciences
Abstract: 

The Hypopituitarism is a chronic clinical condition of multifactorial etiology, defined as the total or partial function loss of the pituitary gland, leading to a poor secretion of hormones from anterior and posterior pituitary gland. Occurs from pituitary, hypothalamus, and surrounding structures diseases. With varying clinical presentation, the hypopituitarism is often insidious; being that the clinical manifestations are determined by the severity, extent and duration of the disease, furthermore, depends on the severity of hormone deficiency. This clinical condition has high morbidity and mortality, and the diagnosis and treatment when instituted early, change the prognosis of the patient. Hormone replacement therapy should be individualized according to the specific needs of each patient. We describe a case in which the patient with pan-hypopituitarism showed an exuberant response to late start of hormone replacement therapy with GH.

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