
A three-month-old male infant was brought to the Department of Pedodontics and Preventive Dentistry with the chief complaint of feeding difficulties. On examination, bilateral cleft lip with complete cleft palate and upper limb deformities were found. In radiographic examination of forearms and chest absent radii and thumb, left rib crowding and neonatal right ventricular hypertrophy were evident. The diagnosis of Holt-Oram syndrome was made based on clinical, radiological and echocardiographic findings. A feeding appliance was fabricated and delivered to the patient.