By us revealed that after shortage of donators and acceptors have been formed the acute necrosis zone owing to disturbance of reaction mediums of “Donators + membrane - redox potentials three - state line system + O2 + АDP + Pi + H+ + nH + membrane space = (ATP + heat energy) + H2O + nH + matrix + CO2” depending on the time of shortage of donators and acceptors in following forms: 1. During 0 - 20 minutes after shortage of donators and acceptors, all cells have not been subjected to damage where the clockwise normal flow of electrons and protons with duration of 4-5 second of every cycle are remained normaly, forming so named normal zone. 2. During 20-30 minutes after shortage of donators and acceptors, some part of cells have been subjected to damage resulting to form of border zone where happened the temporarily stop of clockwise normal flow of electrons and protons with anti – clockwise, antispiral-like evolutionary back steps from second evolution late time equation of flow of electrons and protons to early evolution first time equation with provocation of release of proton, electron from glucose by glycolysis, which followed by transfer of proton, electron to NAD, formation of NADH and substrate phosphorylation accompanied by biosynthesis of ATP without participation of membrane redoxy potential 3 state system, oxygens, ATP synthase with formation of end product as pyruvate . 3. During 30 minutes after shortage of donators and acceptors formed the full necrosis zone where have been observed the complete stop of clockwise normal flow of electrons and protons.
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