CALL FOR PAPERS

CERTIFICATE

IMPACT FACTOR 2018

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

Gender impact on insulin like growth factor 1(igf-1) and selected biochemical markers in iraqi patients with multiple sclerosis

Author: 
Fadwa Ghassan, Dr. Sarwer Jamal Al-Bajalan and Dr.Thamer Mutlag Jasim
Subject Area: 
Health Sciences
Abstract: 

Objective: To investigate the gender impact on serum IGF-1, Vit. D and other clinical parameters in multiple sclerosis (MS) patients and compare between the studied parameters before and after treatment. Design: Thirty Iraqi newly diagnosed patients with MS and follow them after one month of treatment (Beta interferon inj. I inj./week) and compare the results with 20 healthy control. Serum IGF-1, Vit.D, S.GOT, S.GPT, Total Cholestrol and Uric acid were measured. Results: In MS patients, The serum IGF-1 demonstrated a lowest level in the female subjects of control [9.50 ng/dl], while it showed an increased level in male [10.22 ng/dl] , but with similar levels (p> 0.05), The mean of IGF-1 also shown no significant difference between female and male MS patients in pre or post-treatment groups [33.7o vs. 37.46 , 19.22 vs. 21.50 respectively].Similar Vitamin D serum levels( 7.59 and 7.39 ng/ml, respectively) in the two groups of pre-treatment patients (Male and Female), and therefore, no significant difference. In contrast, the controls demonstrated a gradual increase of Vit D. serum level (27.83 and 30.77ng/ml, respectively) in the male and female groups, Such difference was not significant (P ≥ 0.05). In the post-treatment patients also, was no significant difference between male and female patients (11.27 vs. 10.99 ng/ml).Neither SGOT nor SGPT showed a significant variation between the two groups of pre-treatment MS patients for male and for female, although a similar level of SGPT was observed in the control groups for male and female respectively, and the post treatment group of MS patients also not observed and difference between male and female (29.92 vs. 30.17, respectively). No significant difference in uric acid serum level (p≥ 0.05) between male and female groups in pre-treatment patients (4.3 and 4.42 mg/dl, respectively). As well as, in post-treatment MS patient, no significant difference was observed between male and female groups (4.92 and 4.72 mg/dl, respectively). The healthy control group show that the uric acid serum level in male (4.41 md/dl) and in female (4.47 mg/dl) and there was no significant difference between them. There was no significant difference in total cholestrol serum level (p≥ 0.05) between male and female groups in pre-treatment patients (175.38 and 181.94 mg/dl, respectively). As well as, in post-treatment MS patients there was no significant difference was observed between male and female groups (170.92 and 170.0 mg/dl, respectively).The control group show that the total cholesterol serum level in male (160.5 md/dl) and in female (177.14 mg/dl) and there was no significant difference between them. Conclusions: The observed increase in IGF-I in patients treated with IFN-beta being of most significance as a potential therapeutic biomarker.MS, occur more frequently in women. Emerging technologies might provide novel methods with the potential to further dissect the genetic and immunological mechanisms causing the observed differences between women and men with MS.

PDF file: 

IJMCE RECOMMENDATION

ONLINE PAYPAL PAYMENT

CURRENT ISSUE

NEWS

CHIEF EDITOR
Rosane Cavalcante Fragoso, Brasil
ASSOCIATE CHIEF EDITOR

   

Jean-Marc SABATIER
Chief Scientific Officer and Head of a Research Group
France

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

EDITORIAL BOARD

Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran