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Glycemic status and dyslipidemia in type-2 diabetes mellitus in the military hospital marrakesh, Morocco

Author: 
Zineddine ET-TAHOURI, Jihane OUSSAGA, Salma AMRANI IDRISSI, Maryem TARMIDI, Abdellah DAMI and Abderrahman BOUKHIRA
Subject Area: 
Social Sciences and Humanities
Abstract: 

Introduction: Dyslipidemia is a major cause of premature mortality, morbidity and high healthcare costs. It has an important impact in terms of public health and most of them are the result of clinical complications secondary to atherosclerotic lesions of arteries. The aim of the study was to understand the pattern of dyslipidemia among the type 2 diabetic adults’ patient and to understand its association with glycated hemoglobin (HbA1c). Materials and Methods: This is a descriptive retrospective cross-sectionalstudy done over one year in the Military Hospital (Marrakesh, Morocco). To assess the relationship between glycemic control (as reflected by HbA1c) and serum lipid profile in type 2 diabetic patients which included a total of 200 type 2 diabetic patients (104 males and 96 females). Results: The sera were analyzed for HbA1c fasting blood glucose (FBG), total cholesterol, triglyceride (TG), high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL) cholesterol. The levels of HbA1c, FBG, and LDL did not differ significantly between males and females. Female patients showed significantly correlation between HbA1c and FBG. There was a highly significant correlation between HbA1c and FBG, both HbA1c and FBG exhibited direct correlations with cholesterol, TG, and LDL and inverse correlation with HDL; the magnitude of significance for all these lipid parameters being greater with HbA1c than FBG. There was a linear relationship between HbA1c and dyslipidemia. The levels of serum cholesterol and TG were significantly higher and HDL significantly lower in patients with poor glycemic control as compared to patients with good glycemic control. Conclusion: The findings of this study showed that HbA1c is useful biomarker of long-term glycemic control, also a good predictor of lipid profile.

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