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High-intensity focused ultrasound with surface cooling non-invasive abdominal subcutaneous adipose tissue reduction

Author: 
Hector Leal Silva, Esther Carmona Hernandez, Angel Perez Blanco, Mariana Grijalva Vazquez, Sugun Lee and Sebastian Leal Delgado
Subject Area: 
Health Sciences
Abstract: 

Background: High-intensity focused ultrasound (HIFU) quickly raises local temperature of subcutaneous adipose tissue, resulting in instantaneous cell death within the targeted area; higher temperatures can be safely applied using contact cooling. Objective: Evaluate safety and performance efficacy of HIFU with surface cooling for Non-Invasive reduction of the subcutaneous adipose tissue (SAT)in the abdomen. Methods: A new HIFU device (LIPOcel™, Jeisys Medical, Inc. Seoul, Republic of Korea) with contact cooling was used to reduce abdominal circumference adipose tissue in 3 treatment modalities. Results: 30 subjects, mean age of 35.4 years underwent one or 2 HIFU treatments. Mean total energy dose was 509.4 J/cm2, 495 J/cm2, and 374 J/cm2 for Groups A, B, and C respectively; whole study mean total fluence was 459.47 J/cm2. Mean waist circumference reduction was 2.95 cm, 2.4 cm, and 3.8 cm for Groups A, B, and C respectively. A significant mean waist circumference reduction of 3.05 cm from baseline was observed. Most subjects (63.3%) reported being satisfied or very satisfied with the results; 80% of the investigators reported satisfactory results. Conclusions: HIFU with surface cooling using high fluence, assessed by standardized waist circumference measurement, is safe and effective for abdominal SAT reduction and noninvasive body sculpting.

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