
Salivary gland protein of Culex quinquefasciatus was obtained by Homology modelling technique. Ramachandran plot analysis showed that the portion of residues falling into the most favoured regions was (90.9 %). Predicted and validated structure is useful in structure based drug designing. Three compounds of Capsicum annum L. were selected through literature survey and Molecular docking studies were done using Schrodinger Mastro software. Results showed that out of three ligands taken from pub chem., Homocapsaicin 6442566 had glide score of -1.9 as compared to phytol 5280435 of -1.46. It was also observed that Capsanthin 5281228 had no glide score.