The development of new medical treatments and cures would not happen without health research and the active role of research volunteers. Behind every discovery of a new medicine and treatment are thousands of people who were involved in health research. Thanks to the advances in medical care and public health, we now live on average 10 years longer than in the 1960's and 20 years longer than in the 1930's. Without research, many diseases that can now be treated would cripple people or result in early death. New drugs, new ways to treat old and new illnesses, and new ways to prevent diseases in people at risk of developing them, can only result from health research. The research proposal is an important step in developing a research project. In the first instance it helps you to further define your research question and enables you to demonstrate how you intend to go about answering that question. Secondly, the research proposal is able to give an overview of the research project so that other people understand the scope of the research, the significance of the research. This Paper attempts to provide the researchers, the various steps involved in formulating a health research protocol.