CALL FOR PAPERS

CERTIFICATE

IMPACT FACTOR 2018

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

An Invtro Study on Anti-Obesity, Antiradical Activities of Siddha Medicine Nathai Choori Chooranam

Author: 
Pitchiah Kumar, M. and Sankaranarayanan, S.
Subject Area: 
Life Sciences
Abstract: 

Traditional systems of medicine have been in trend for treating numerous ailments in many develop and development countries such as India, China, Japan and Korea, Tavian since age-old time. Siddha system of medicine is one of the ancient traditional system of India and practiced mostly in its southern part of India for treating different diseases including even chronic conditions. Nathai choori chooranam composed of five plant equal composition (Borreria hispida seed, Zingiber officinale Rhizome, Cassia auriculata flower, Anddry fruit and Eleusine coracana seed). Plants offer us bioactive molecules those may serve as safer therapeutics to combat existing new world ageing related diseases, and obesity is the major concern among them. Pancreatic lipase inhibitors from plant sources may prove as promising side effects lacking anti-obesity therapeutics, present study was conceived with the objective of anti-lipase, antiradical and DNA cleavage protector activities of Nathai choori chooranam decoction. Phytochemical constituents were screened quantifications of total phenolics, tannins, flavonoids, were done by taking tannic acid, quercetin, as reference molecules. Antiradical activities were evaluated by using different free radicals (ABTS, lipid peroxidation, metal chelating, superoxide and nitric oxide scavenging activities). Also effect of Nathai choori chooranam decoction on DNA cleavage induced by H2O2 UV-photholysis. The antiradical activity of Nathai choori chooranam decoction was proved to be better than the standard ascorbic acid. Antilipolytic function of Nathai choori chooranam decoction was assessed using porcine pancreatic lipase (PPL; triacylglycerol lipase, EC 3.1.1.3) in an in vitro assay system with p-nitrophenyl palmitate (p-NPP) as a substrate. From the data of the results obtained, maximum percentage of lipase inhibition was shown by Nathai choori chooranam decoction (78.92 %) than standard drug. In addition, they showed a protective effect on DNA cleavage.IC50 value were calculated using the logarithmic regression of the dose-response curve after subtraction of both blank and inherent sample fluorescence values. In all cases, the coefficients of determination of the regression (R2) were greater than 0.95. IC50 are the means ± standard deviations of three determinations.

PDF file: 

IJMCE RECOMMENDATION

ONLINE PAYPAL PAYMENT

CURRENT ISSUE

NEWS

CHIEF EDITOR
Rosane Cavalcante Fragoso, Brasil
ASSOCIATE CHIEF EDITOR

   

Jean-Marc SABATIER
Chief Scientific Officer and Head of a Research Group
France

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

EDITORIAL BOARD

Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran