Background and purpose: Dengue virus is the fastest growing vector-borne disease today. According to the Centres for Disease Control and Prevention (CDC), there are an estimated 400 million dengue infections each year in over 125 countries. The purpose of the present study is to assess the level of Knowledge and Practice about Dengue Fever among people. Materials and Method: A Quantitative descriptive design was adopted for the study. Health centres were selected randomly and a total of 60 samples were selected using convenience sampling technique. Structured questionnaire with interview schedule and 5 point rating scale was used to collect the data. For analyzing the data, descriptive statistics (frequency, percentage, mean and standard deviation) were used. Results: The result revealed that 33(55%) samples had fair knowledge, 27(45%) had good knowledge on dengue fever, 57(95%) samples had good practice and only 3(5%) had very good practice on Dengue Fever. Conclusion: The present study revealed that the level of Knowledge was fair but their Practice was good among peopleto control and prevent Dengue fever.