CERTIFICATE

IMPACT FACTOR 2021

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Low pressure hyperbaric oxygen therapy in autism spectrum disorders: A prospective, randomized study of 30 children

Author: 
Vecchione, R., Picariello, N., Haidar Hassan, K., Del Corso, F., Corcos, L., Nappi, A., Mauro, U. and Antonucci, N.
Subject Area: 
Health Sciences
Abstract: 

Background: Hyperbaric Oxygen Therapy (HBOT) is a recommended treatment for all hypoxic-ischemic pathologies. It has been demonstrated that perfusion abnormalities are present in some areas of cerebral grey matter in autistic children and there is a lack of connectivity in areas of the white matter. The cause of these anomalies is still unknown. The areas involved (temporal lobes, frontal lobes, and other areas such as the thalamus, limbic circuits, corpus callosum, and cerebellum) are connected to the symptoms and behavior of these patients. The PET and SPECT scans demonstrate how low pressure HBOT facilitates the oxygenation of hypoxic cerebral areas in autistic children. The clinical trials recorded in the literature are still insufficient for clarifying many elements. Goals: To demonstrate that HBOT leads to significant improvements in specific abilities and behavioral symptoms tied to the functioning of the affected brain areas, and to show the safety of the HBOT treatments. Materials and Methods: Thirty children between five and nine years old, randomized, with autism spectrum disorder (ASD) underwent HBOT at 1.5 ATA and 100% oxygen for a total of 40 sessions. The following eight psychometric scales were used for the analysis: VMI (Visual-Motor Integration), PPVT (receptive-auditory language), BRIEF (executive function), SRS (social responsiveness scale), VABS (adaptive behavior), ABC (aberrant behavior), PSI (parental distress index), A.T.E.C. (analysis of treatment outcomes). Multiple statistical tests were used, based on the requirements of each specific analysis. Results: Improvement was found in the following areas/abilities: receptive-auditory vocabulary (p=0.016), visual-motor integration (p=0.045), visual perception (p= 0.004), motor coordination (p=0.049), “SHIFT” scale (p=0.013), subscale I/irritability (p=0.001), subscale II/lethargy (p=0.015), subscale III/stereotypic behavior (p=0.040), subscale IV/hyperactivity (p=0.000), subscale V/inappropriate speech (p=0.008) on the ABC test, communication scale (p=0.000), global scale of adaptive behavior (p=0.001), and in the outcomes of the treatment (p=0.029). A decrease was found on the social awareness subscale (p= 0.21). The analysis of the ABC subscale revealed that there were also significant improvements during the course of the treatment. Conclusions: A significant probability of obtaining positive clinical results using HBOT in subjects affected by ASD was demonstrated. No side effects were observed in any of the children who were treated.

PDF file: 

CALL FOR PAPERS

 

ONLINE PAYPAL PAYMENT

IJMCE RECOMMENDATION

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

 

EDITORIAL BOARD

CHUDE NKIRU PATRICIA
Nigeria
Dr. Swamy KRM
India
Dr. Abdul Hannan A.M.S
Saudi Arabia.
Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran