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Molecular profiling in early onset gastric malignancies- a case series

Author:

Dr. Murugesan, N., Dr. Veena Bheeman, Dr. Visvanathan, M.S., Dr. Uday Khumbar and Dr. Anbazhakan, R.

Subject Area:

Health Sciences

Abstract:

We have encountered three cases of advanced gastric malignancies in persons in their early twenties. All three tumours were reported by histopathology to be poorly differentiated adenocarcinomas with signet cells and one among them also had a neuroendocrine component, proven by immunohistochemistry. They all had aggressive disease and were the first cases in their respective families. The presentation of these patients, molecular profile of the tumour and management will be discussed.

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