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Nasal Anatomy and Absorption through Nasal Route

Author: 
Diksha Sharma and Shweta Agarwal
Subject Area: 
Health Sciences
Abstract: 

The nasal cavity is covered by a thin mucosa which is well vascularised. This facilitate to quick transfer of drug molecules across the single epithelial cell layer directly to systemic blood circulation without first-pass hepatic and intestinal metabolism. In this way the effect of a smaller drug molecule can be achieved in five minutes. The nasal administration therefore can be used a better route than oral drug administration. The present study is all about the compilation of existing knowledge about nasal anatomy and mecahahis routnism of absorption through nasal rout nase. The study is also about the present formulations for nasal administration.

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