The cleidocranial dysplasia is a rare disease which can occur in either sex equally or by autosomal dominant trait. Problems associated with this condition are multiple supernumerary teeth, retained deciduous teeth, delayed eruption, change in shape, impacted teeth and absence of deciduous teeth resorption. For the management of Cleidocranial dyaplasia with many clinical conditions various orthodontic-surgical regimes are discussed in literature. Here we report a rare case of cleidocranial dysplasia in a 25 year old female patient with a new orthodontic- surgical approach which is more adaptive and useful for interdisciplinary management.