CALL FOR PAPERS

Author Information

CERTIFICATE

IMPACT FACTOR 2021

Subject Area

Life Sciences / Biology
Architecture / Building Management
Asian Studies
Business & Management
Chemistry
Computer Science
Economics & Finance
Engineering / Acoustics
Environmental Science
Agricultural Sciences
Pharmaceutical Sciences
General Sciences
Materials Science
Mathematics
Medicine
Nanotechnology & Nanoscience
Nonlinear Science
Chaos & Dynamical Systems
Physics
Social Sciences & Humanities

Why Us? >>

Open Access
Peer Reviewed
Rapid Publication
Life time hosting
Free promotion service
Free indexing service
More citations
Search engine friendly

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

One-pot synthesis, antibacterial, dna photocleavage and sar studies of some fused 1,4-dihydropyridines via symmetrical hantzsch condensation

Author:

Manvinder Kaur and Harvinder Singh Sohal

Subject Area:

Physical Sciences and Engineering

Abstract:

Fused carbo/heterocyclic 1,4-dihydropyridine (1,4-DHPs) derivatives have been synthesized using β-cyclodextrin an efficient catalyst in alcohol with high yields and purity under one-pot method. The structures of synthesized compound were established using 1H, 13C-NMR, IR, ESI-MS and elemental analysis. The synthesized fused heterocyclic 1,4-DHPs were found to exhibit potent antimicrobial activity as compared to carbocyclic 1,4-DHPs and these results were further supported by percentage structure similarity using Chem 3D software with the standard antibiotic drug (Cefixime). Moreover, heterocyclic 1,4-DHPs shows excellent DNA photocleavage potential using agarose gel electrophoresis.

PDF file: