Oral lesions – the clue to diagnosis of the most common blistering disease

Pemphigus Vulgaris is a chronic autoimmune intradermal blistering mucocutaneous disease that initially manifests in the form of intraoral lesions, followed by other mucous membranes and the skin. The aetiology of the disease still remains unclear but the presence of auto antibodies is consistent with an autoimmune disease. Systemic corticosteroids remain the treatment of choice but topical corticosteroids are also used for long term non-healing lesions of the oral cavity. In this article, we have discussed a case of a 60-year-old woman showing oral ulceration without skin lesions.