The most common, convenient and preferred route of drug administration is oral route. Oral disintegrating tablets are the solid dosage forms that disintegrates in the saliva in less than 60 seconds, and are thus taken without the need of extra water. The oral disintegrating tablets are launched in 1980 and hence now-a-days it is one of the fastest growing segment of oral dosage form due to its improved solubility, stability and patient compliance. The versatile manufacturing technologies of orally disintegrating tablet is now no longer limited by dosage strength, bitter active pharmaceutical ingredients (API) and narrow therapeutic applications. scientists have prepared ODTs by following various methods like compression, molding, melt granulation, phase transition process, sublimation, freeze-drying, spray drying, effervescent methods etc.