Exclusive breastfeeding in infants in Indonesia is only 40.6%, this is still below the national target of 80%. Inhibiting factors in breast feeding is the breast milk production itself. Less and slowly production of breast milk can causes the mothers not give enough milk to her baby. The aim of the study was to determine the relationship of oxytocin massage and breast care with breast milk production. The research is a quantitative analytic with cross sectional approach. The research sample was 100 breastfeeding mothers in the of Bulili Public Health Center area. Sampling taken by accidental sampling method. Data collection is done by observation and interview using questionnaire and analyzed with Chi Square test. The results showed that there was a relationship between oxytocin massage (p = 0.001) and breast care (p = 0.012) with breast milk production. According this research result can be concluded that oxytocin massage and breast care has a relationship with breast milk production. It is recommended that public health center to provide socialization regarding the importance of oxytocine massage and breast care for mothers to increase breast milk production.