Pancreatic stem cells: The hope (sources – marker expression– promising applicationsin regenerative medicine)

The potential of stem cells in regenerative medicine to combat diabetes is an excitingpurpose. From beta cell replacement to immune modulation and vascular regeneration, stem cell-based approaches offerhope for more effective treatments and a potential cure for this widespread metabolic disorder. As research in this field continues to advance, stem cell therapies may revolutionize the management of diabetes, offering new possibilities for improved quality of life for patients.In this review, although some significant technical hurdles remain, stem cells offer great hope for patients with diabetes. This review will provide insightson the sources and marker expression of pancreatic stem cells. The data are collected about the potential use of pancreatic stem cells (PSC)-derived islets for treating and understanding types of DM. Induced pluripotent stem cells (iPSCs), are promising for the treatment of diabetes owing to their self-renewal capacity and ability to differentiate into functional β-cells.Type 2 diabetes patients might benefit from the transplantation of cells expanded from their own duct cells since they would not need any immunosuppression.