
Cleome viscosa L. is a plant widely used to treat various diseases and grows on degraded or marginal agricultural lands. This study is aimed to investigate the phytochemical screening and anti-radical activity of Cleome viscosa.An ethnobotanical survey was conducted. Alkaloids were checked using BOUCHARDAT reagent and flavonoids were detected using SHINODA reagent. The 1,1-Diphenyl-2-Pycril Hydrazil (DPPH) free radical scavenging and the Ferric-Reducing Antioxidant Power (FRAP) assays were used to highlight the antioxidant activities. The ethnobotanical investigations conducted show that women (57%) uses more Cleome viscosa than men (47%) to fight diseases. Phytochemical screening revealed that Cleome viscosa contains alkaloids, flavonoids, saponins and tannins.The DPPH free radical value is 16.18± 0.024 mg of quercetin per gram of plant material and the FRAP value is 986.88± 0.012 μmol/L equivalent in Fe2+ per gram of plant material. Our result shows that Cleome viscosa possesses phytochemical compounds and anti-radical activity.