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Predictors of glycemic control in children with type 1 diabetes mellitu

Author: 
Dr. Nileena Paul, Dr. Deepa Anirudhan, Dr. Lathika Nayar and Dr. K. K. Purushothaman
Subject Area: 
Health Sciences
Abstract: 

Introduction: Type 1diabetes mellitus is a common chronic endocrine disease with increasing incidence in India. Improved glycemic control in children with type 1 diabetes mellitus delays the progression of microvascular complications. Aim: To identify the factors and predictors associated with glycemic control in children and adolescents with type 1 diabetes. Materials and Methods: An analytical cross sectional study was conducted on 40 children with Type 1 diabetes mellitus attending our diabetic clinic. These children were classified as having good glycemic control and poor glycemic control according to the target level of HbA1c <7.5% and >7.5% respectively. Demographic factors and disease-related characteristics were analysed. HbA1C, Serum TSH and lipid profile were done. Results: Among 40 children enrolled in study mean age was 12.52 years with male: female sex ratio as 1:1.67. We had 11 (27.5%) children with good glycemic control and 29 (72.5%) children with poor glycemic control. Younger age of patient at study, younger age at onset of disease, frequent blood glucose monitoring, good dietary control were associated with good glycemic control in children with Type 1 diabetes. Prolonged duration of disease, higher mean cholesterol, higher triglycerides, higher LDL and low HDL were associated with poor glycemic control. Conclusion: Younger age of patient at study, younger age at onset of disease, frequent blood glucose monitoring, good dietary control were associated with good glycemic control in children with T1DM. Prolonged duration of disease, higher mean cholesterol, higher triglycerides, higher LDL and low HDL were associated with poor glycemic control in children with Type1 diabetes.

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