Although numerous studies have been done worldwide, there is limited data available on demographic profile of fungal osteomyelitis in the North Karnataka population. This study was designed to evaluate the prevalence of fungal osteomyelitis of the jaws associated with diabetes mellitus in North Karnataka population over a period of 10 years. Histologically diagnosed cases of osteomyelitis of the jaws were reviewed from January 2005 to December 2015 and subjected to statistical analysis by Chi-square test for age, gender, site, area and diabetic status. 52% cases were that of fungal osteomyelitis whereas, 48% belonged to non- fungal osteomyelitis. Fungal osteomyelitis was frequently found above 40 years of age (80.76%), more commonly in males (69.23%) and affecting the maxilla (80.76%). It was also noted that fungal osteomyelitis of the jaws was more commonly associated with diabetes mellitus (61.53%).