PRF is an excellent autogenous biomaterial used in the field of dentistry in recent times, with predictable results. PRF is a second-generationplatelet concentrate, which has several advantages over traditionally prepared PRP. PRF is now considered as an autogenous biomaterial, which has abundant growth factors and cytokines, entrapped in fibrin matrix, which creates an ideal environment for perfect wound healing and tissue regeneration. This article describes the properties, procurement and its various applications in the field of dentistry.