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Primary mucinous adenocarcinoma of the vagina: a case report

Author: 
Salhi, H., Jaidane, O., Ayadi, M.M., Hassouna, J.B., Dhiab, T., Hechiche, M. and Rahal, K.
Subject Area: 
Health Sciences
Abstract: 

Background and aim: Primary mucinous carcinoma of the vagina is a rare disease which is characterized by aggressiveness and relative resistance to conventional treatment modalities. We aim to report a new case of this rare entity, to investigate its characteristics and its prognostic factors. It is a case of advanced stage of primary mucinous adenocarcinoma of the vagina, diagnosed in our service in January 2015, showing a highly aggressive course. Case: A 35 year old woman was admitted to our institute to be treated for advanced stage primary mucinous adenocarcinoma of the vagina. She had no history of in utero exposure to diethylstilbestrol. A digestive endoscopy and a colonoscopy were normal. She was treated by three courses of neoadjuvant chemotherapy with tri-weekly paclitaxel and carboplatin which were partially effective. However, the disease progressed rapidly and the patient died four months after the treatment. Conclusion: Recognition of this rare entity is important and additional data about patients with primary mucinous carcinoma of the vagina should be collected and analyzed to better characterize these tumors and to elucidate its prognostic factors, optimal treatment and outcome.

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