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Protective effect of quercetin in lps induced mitochondrial cell injury

Author: 
Swati Sharma, Dr. Parihar, M. S. and Dr. Abha Swarup
Subject Area: 
Life Sciences
Abstract: 

We all know proper cell functioning needs energy which will be provided by Mitochondria. Sometimes some bacterial infections like Lip Opolysaccharide (LPS) affects these functions of cell by degrading mitochondrial biogenesis. LPS infection increases ROS (Reactive oxygen species) production which affects H9C2 cells contractility and functions and leads to degraded heart health. But as protective agent quercetin pre-treatment to cells provides safety from these types of infections in H9C2 cells. In our study we have focused on increased ROS production due to LPS induced inflammation and found protective effects of quercetin on pre-treated H9C2 cells.

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