Recurrent aphthous stomatitis: a case series

Recurrent Aphthous Stomatitis is the most frequent ulcerative disorder observed in the oral cavity. The aetiology is unknown, but several predisposing factors have been identified as possible causes. These including local, immunologic, allergic, genetic, nutritional or microbial current events. In most cases the disorder is localized but in others, it can be a clinical sign of systemic diseases such as Behçet’s disease , or gastrointestinal disorders (Celiac Disease, Crohn’s disease, ulcerative rectocolitis) or congenital and acquired immunodeficiency (including HIV infection) and such conditions should therefore be sought and excluded. Here we presented our experience of twenty-one subjects aged between 0 and 12 years evaluated over a period of two years. In this study we aimed to define the clinical features of aphthous ulcers in children with accompanying clinical and laboratory findings supposed to be related to the disease. In our experience one was affected by periodic fever aphthous stomatitis pharyngitis , two were affected by Beçhet’s disease and one by Crohn’s disease.