Rickettsial and related infections are infectious, re-emerging, polymorphic, life-threatening and globally prevalent diseases. These pathologies prevail in Guinea in several forms with a variation of the etiological agents. The objective of this study was to identify the infectious agents responsible for rickettsial diseases and related diseases in the regions of Kindia and Mamou. The investigation work was carried out from January 6, 2016 to February 6, 2017. A total of 6 types of infectious agents were found by PCR, 2 at Mamou Coxiella burnetti and Bartonella spp. and 4 to Kindia Coxiella burnetti, Borellia burgdorferi, Borellia burgdorferi. The frequency of Coxiella burnetti rickettsiosis was 84.22% in the 2 target regions. For related infections the overall prevalence was 5.26% for rickettsial disease with Bartonella spp. 5.26% with Q Fever and 5.26% with Lyme Borellia burgdorferi disease. The vectors were overall Ripicephalus decoloratus (Coxiella burnetti and Bartonella spp. Rickettsiosis), Amblyomma variegatum (Crimean-Congo hemorrhagic fever). The presence of ticks on livestock is a factor in the spread of rickettsial diseases in regions in Guinea. Particular attention should be paid to these pathologies by the public and veterinary health services.
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