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Review Article On The Management Of Pancreatic Fistulae

Author: 
Islam, S., Seetahal-Maraj, P., Dan, D. and Naraynsingh, V.
Subject Area: 
Health Sciences
Abstract: 

Introduction: The most significant cause of morbidity and mortality after pancreatic resection, either for malignancy or certain benign disorders, is the development of pancreatic leak and pancreatic fistula. Fistula formation is multifactorial and is often influenced by patient-specific anatomic features of the pancreas and operative techniques at the time of resection.Various strategies have been employed to decrease its incidence including pharmacologic manipulation, and modifications and refinements in surgical technique. Methods: A broad PubMed and Cochrane database search was conducted, on pancreatic fistula, post-operative fistula, and the various techniques in management. Conclusions: It is clear that early recognition of pancreatic fistula (PF) and prompt institution of appropriate treatment is the cornerstone in the prevention of potentially devastating consequences. While there are multiple surgical techniques and novel therapies, none have proven to be the gold standard thus far.

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