Acute appendicitis is common abdominal surgical emergency. It is usually seen in teenagers. Acute appendicitis is diagnostic challenge for any surgeon, because many disease simulate acute appendicitis. Diagnostic difficulty with atypical findings resulted in unnecessary appendicectomy. Many studies shown that appendicitis associated with elevated C Reactive protein. When elevated C Reactive protein is associated with leucocytosis is more specific for appendicitis. Normal C Reactive protein associated with normal appendix.