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Serum lipid profile and ferritin in β- Thalassemia trait patients

Author:

Suresh Babu, T V., Saritha and Manjula Shantaram

Subject Area:

Life Sciences

Abstract:

Introduction: Thalassemia is one of the heterogenic groups of inherited anemia which occurs mainly dueto mutation in the gene related to the synthesis of hemoglobin beta- chains. Objectives: The aim of our study was to evaluateserumlipid profile andferritin levels in β- thalassemia trait (BTT) and compare them with that ofage and sex matched controls. Methodology: Totally 120 young adults were selected for the study, in which 60 wereBTT and other 60 were healthy controls. Serum lipid profile was analyzed using ERBA kit and serum ferritin was estimated withMeril Diagnostic kit. Results: Total cholesterol and LDL values were lower in BTT when compared to controls and TG and HDL values were higherin BTT with that of controls.Serum ferritin values were found to be higher in BTT than that ofcontrols. Conclusion: The presentstudy revealed that there were significant changes in serum lipid profile and ferritin levels in BTT when compared to controlswhich should be a cause for anxiety of better assessment of cardiovascular risk factors in the patients.

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