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In silico screening and in vitro analysis of cervical cancer cells in Hela cell line via Chrysophyllumcanito leaf

Author:

Antony Y. Prabhu and Shamina, S.

Subject Area:

Life Sciences

Abstract:

In silico screening is a study of systems biology commences by computer along with proteins and chemical compounds. Diverse types of cancer responsible proteins were analyzed under schrodinger suite such as PTEN, NKCR, BRCT7 and BRCT8, Chek1, BRCA, Rad51D, BRCA1, HSP27 and HSP70. Proteins study revealed the maximum anti-cancer effects of cervical cancers. Chrysophyllumcanito plant chemical compounds roles were annotated by means of systems biology with strong evidence. In vivo analysis was obviously demonstrated the heat shock protein 70 kilo dalton role in cervical cancer via the HeLa cell line.

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