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Solid support synthesis of thiazolo-pyrazoline derivatives and evaluation of their antimicrobial activities

Author:

Sumeet Kaur, Ramandeep Kaur, Balbir Kaur, and Mohamad Yusuf

Subject Area:

Life Sciences

Abstract:

The microwave-assisted synthesis of thiazolo-pyrazoline derivatives was carried out, using silica gel as solid support i.e. through an eco-friendly technique. Keeping in view of the wider therapeutic applications of these derivatives, they are screened for antibacterial activities against E.coli, Klebsiella pneumonia, Pseudomonas aeruginosa, S.aureus and B.subtilis strains and for antifungal activities against Aspergillus janus and Pencilliun glabrum strains using amoxicillin and fluconazole as standard drugs respectively.

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