CALL FOR PAPERS

CERTIFICATE

IMPACT FACTOR 2018

Subject Area

  • Life Sciences / Biology
  • Architecture / Building Management
  • Asian Studies
  • Business & Management
  • Chemistry
  • Computer Science
  • Economics & Finance
  • Engineering / Acoustics
  • Environmental Science
  • Agricultural Sciences
  • Pharmaceutical Sciences
  • General Sciences
  • Materials Science
  • Mathematics
  • Medicine
  • Nanotechnology & Nanoscience
  • Nonlinear Science
  • Chaos & Dynamical Systems
  • Physics
  • Social Sciences & Humanities

Why Us? >>

  • Open Access
  • Peer Reviewed
  • Rapid Publication
  • Life time hosting
  • Free promotion service
  • Free indexing service
  • More citations
  • Search engine friendly

Plagiarism Detection

IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.

Speciation of candida and antifungal susceptibility testing from clinical specimens in a tertiary care hospital, Bangalore

Author: 
Dr. Bhavana, C., Dr. Nagarathnamma, T and Dr. Ambica, R.
Subject Area: 
Health Sciences
Abstract: 

Objective: Candida albicans is generally considered the major pathogen among the Candida species. An increase in the prevalence of non-albicans Candida species has been noted during the last decades and also azole resistance is seen more commonly in non-albicans Candida species compared to Candida albicans. The objective of the study was to identify, isolate and speciate Candida and perform antifungal susceptibility testing from various clinical specimens which has a direct impact on choice of empirical antifungal treatment. Methodology: A total of 100 Candida isolates from various clinical specimens were processed for speciation using standard mycology methods. Antifungal susceptibility testing was performed by disc diffusion method according to CLSI guidelines M44-A2. Results: The present study had a male preponderance, with an overall male: female ratio being 1.4:1. Isolation of Candida was highest among the extremes of age group i.e., neonates followed by 50-70 yrs. The various species of Candida isolated in the study were C.tropicalis (39%), C.albicans (35%), C.krusei (13%), C.glabrata (7%) and C.parapsilosis (6%). There was variation in the susceptibility pattern of Candida spp. to frequently used antifungal drugs. The Candida species showed highest sensitivity to Nystatin (98.92%) and Amphotericin B (84.95%) followed by Fluconazole (42.53%), Clotrimazole (30.12%) and Ketoconazole (25.8%). C.tropicalis, C.albicans and C.parapsilosis were 100% sensitive to Nystatin. C.krusei was 100% sensitive to Clotrimazole and 92.3% sensitive to Amphotericin B and Nystatin. The susceptibility of C.albicans to fluconazole was only 60%. Conclusion: Non-albicans Candida is gaining clinical significance. Hence identification of species will be helpful in selection of antifungals for the earlier and cost effective treatment. CHROM agar serves as a primary isolation and differentiation medium for clinical specimens that could allow laboratories to rapidly identify Candida spp, enabling clinicians to choose appropriate antifungal agents, thus decreasing patient’s morbidity and mortality.

PDF file: 

IJMCE RECOMMENDATION

ONLINE PAYPAL PAYMENT

CURRENT ISSUE

NEWS

CHIEF EDITOR
Rosane Cavalcante Fragoso, Brasil
ASSOCIATE CHIEF EDITOR

   

Jean-Marc SABATIER
Chief Scientific Officer and Head of a Research Group
France

Advantages of IJCR

  • Rapid Publishing
  • Professional publishing practices
  • Indexing in leading database
  • High level of citation
  • High Qualitiy reader base
  • High level author suport

EDITORIAL BOARD

Luai Farhan Zghair
Iraq
Hasan Ali Abed Al-Zu’bi
Jordanian
Fredrick OJIJA
Tanzanian
Firuza M. Tursunkhodjaeva
Uzbekistan
Faraz Ahmed Farooqi
Saudi Arabia
Eric Randy Reyes Politud
Philippines
Elsadig Gasoom FadelAlla Elbashir
Sudan
Eapen, Asha Sarah
United State
Dr.Arun Kumar A
India
Dr. Zafar Iqbal
Pakistan
Dr. SHAHERA S.PATEL
India
Dr. Ruchika Khanna
India
Dr. Recep TAS
Turkey
Dr. Rasha Ali Eldeeb
Egypt
Dr. Pralhad Kanhaiyalal Rahangdale
India
DR. PATRICK D. CERNA
Philippines
Dr. Nicolas Padilla- Raygoza
Mexico
Dr. Mustafa Y. G. Younis
Libiya
Dr. Muhammad shoaib Ahmedani
Saudi Arabia
DR. MUHAMMAD ISMAIL MOHMAND
United State
DR. MAHESH SHIVAJI CHAVAN
India
DR. M. ARUNA
India
Dr. Lim Gee Nee
Malaysia
Dr. Jatinder Pal Singh Chawla
India
DR. IRAM BOKHARI
Pakistan
Dr. FARHAT NAZ RAHMAN
Pakistan
Dr. Devendra kumar Gupta
India
Dr. ASHWANI KUMAR DUBEY
India
Dr. Ali Seidi
Iran
Dr. Achmad Choerudin
Indonesia
Dr Ashok Kumar Verma
India
Thi Mong Diep NGUYEN
France
Dr. Muhammad Akram
Pakistan
Dr. Imran Azad
Oman
Dr. Meenakshi Malik
India
Aseel Hadi Hamzah
Iraq
Anam Bhatti
Malaysia
Md. Amir Hossain
Bangladesh
Ahmet İPEKÇİ
Turkey
Mirzadi Gohari
Iran