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To study and correlate the levels of serum uric acid in patients with primary hypertension

Author: 
Dr. Aher Sangeeta, Dr. Ashok kumar and Dr. Rahul Gutte
Subject Area: 
Health Sciences
Abstract: 

Introduction: The association between arterial hypertension (HT) and hyperuricemia is very common. It has been reported that 25-40% of patients with untreated HT and more than 80% of patients with malignant HT have high SUA levels .Hypertension has itself been recognized as an independent risk factor for cardiovascular mortality and morbidity .Normal values of serum uric acid for women are 2.5 to 7.5 milligrams/deciliter (mg/dL) and for men 4.0 to 8.5 mg/dL. SUA and blood pressure are such two indicate to a possible correlation between them which further needs to be elaborated in Indian scenario. Materials and methods: This was a cross-sectional, observational, comparison study in the normotensive and hypertensive patients visiting medicine outpatient department at a tertiary healthcare setup. A total of 100 patients were studied. Patients were enrolled into two groups, Group 1: Hypertension and group 2: Normal control. Each group was allotted 50 participants. The patients were included if they satisfied the JNC VII criteria for hypertension. They were excluded if they were having any other condition known to cause raised serum uric acid levels and secondary hypertension. Results: With the result based on the study carried out we concluded that there can be a direct relation between hyperuricemia and hypertension. Also the study showed that the SUA levels were significantly increased in patient with stage 2 hypertension in comparasion with those with stage 1 hypertension, showing that the severity of hypertension also related to the SUA levels. Conclusions: Based on the study carried out we concluded that SUA can be used as an early biochemical marker to determine the severity and duration of hypertension.

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