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To study the effect of addition of nalbuphine to intrathecal bupivacaine used for elderly patient in lower abdominal surgeries under spinal anaesthesia: A randomised double blinded control study

Author: 
Dr. Sanjay P. Gadre and Dr. Asif Sayeed
Subject Area: 
Health Sciences
Abstract: 

Background and Objectives: The purpose of this study was: 1. To asses, evaluate and compare the analgesic effect of intrathecal nalbuphine when added to hyperbaric intrathecal bupivacaine and bupivacaine alone. 2. To evaluate the onset, quality and duration of sensory and motor blockade achieved with hyperbaric bupivacaine and nalbuphine combination when administered intrathecally for spinal anesthesia in lower abdominal surgery. 3. To study the effect of intrathecal nalbuphine on vital parameters. 4. To study any side effects and complication. Methodology: 40 ASA I and II patients of age group 50-70 years, scheduled for below umbilicus surgeries were chosen for this study. Patients were randomized in two equal groups of 20 each by lottery method. Group I (Study Group) received 3 ml of hyperbaric bupivacaine 0.5 % + 0.5 ml inj. nalbuphine (0.5 mg) intrathecally. Group II (Control Group) received 3 ml of hyperbaric bupivacaine 0.5 % + 0.5 ml of inj. normal saline intrathecally. Assessment of motor and sensory blockade was done by Bromage scale and pin prick method. Pulse rate, BP, respiratory rate and SpO2 were monitored throughout intraoperative period and 24hrs postoperative period. Results: There is no significant difference between 2 groups for onset of motor and sensory blockade but mean time of postoperative analgesia in Study Group was highly significant than Control Group. No patient in our study developed any side effects. Conclusion: Nalbuphine provides better quality of block as compared to bupivacaine alone. It also prolongs postoperative analgesia when used as adjuvant to spinal bupivacaine in elderly patients.

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