
The rapid emergence of more and more resistant strains of microorganisms is a matter of concern for the scientists world over. As the advances in science are coming up with better and better antibiotics, the irrational use by the clinicians for fast relief makes them ineffective and resistant as the organisms mutate in their genetic process. The emergence of MRSA and multidrug resistant strains of most bacteria such as Superbug’s has become an utmost challenge to mankind. Bone infection is resistant to treatment due to multiple reasons inherent to bone itself. Therefore, before the infective organisms make deep inroads in the bone, it’s important to recognise these microbes early when they are superficial and put the patients on appropriate bactericidal drugs to which they are sensitive, for adequate length of time so as to ensure complete recovery. The present study gave us overall insight to the prevalence of various microorganisms and their sensitivity and resistance pattern, in our region. The study highlighted that Staphylococcus aureus was more prevalent in bone infections (29.1%) and MRSA formed 35.7% of it. Another factor to take care was high prevalence of Gram negative organisms with high percentage of resistant strains (14%).