• To study the epidemiology of the solitary nodule of the thyroid. • To study the role of fine needle aspiration cytology in the management of solitary nodule of the thyroid. • To study the incidence of malignancy in solitary nodule of the thyroid. Materials and Methods Case selection All patients admitted with a solitary nodule of the thyroid. Exclusion criteria • Patients with severe comorbid illness. • Patients with solitary nodule of thyroid and regional lymph adenopathy. Materials and Methods Place of study: Thanjavur medical college hospital, Thanjavur. Period of study: 31.01.2014 to 31.01.2016- 2 years No of patients: 100 A total of (110) consecutive patients admitted at TMCH, Thanjavur with solitary nodule of the thyroid and only 100 of the patients who satisfied the above criteria were included in the study. Limitation of the study: Many patients are lost to follow up after 2 reviews and the exact incidence of post operative hypothyroidism could not be evaluated.