A Holstein Friesian mal¬¬e cattle consumed Lantana leaves 2 days back and was presented with the symptoms of dullness, depression, anorexia, dry parchment like skin, lethargy and icteric mucous membrane. It was diagnosed as a case of photosensitization due to consumption of Lantana camara. However, the animal was treated with 500 ml of 5% dextrose normal saline mixed with 15 ml of B complex Vitamin supplements intravenously, Meloxicam @ 0.5 mg/kg intramuscularly and Avil @ 0.5 mg/kg intramuscularly for a week . Livotas syrup was advised to be given orally once a day @ 30ml for one month. External antiseptic ointments were applied daily for skin lesions. The duration of therapy for the complete clinical recovery was 30 days.