Mechano heterocyclic chemistry (MHC) is a recent and quickly growing technique in synthesis of heterocycles. Benzo[b]1,4-thiazepines,benzo[b]1,4-diazepines\were prepared via new mechano-chemical (grinding)technique of α,β-epoxyketoneswith o-aminothiophenol, and o-phenylenediamine, respectively. The same compounds were synthesized under conventional thermal method. However, quinoxalines were obtained from α,β-epoxyketones and o-phenylenediamine, mainly under conventional method. We introduced the yield economy [YE] as a metric to assess the conversion efficiency of grinding and conventional synthetic reactions. Notably, the mechano-chemical reaction provides a green facile access of thiazepines, diazepines,andquinoxalines in excellent yields, as well as providing higher yield economy [YE] compared with conventional thermal methods. The antimicrobial activity of some of the synthesized heterocycles was tested.
IJCR is following an instant policy on rejection those received papers with plagiarism rate of more than 20%. So, All of authors and contributors must check their papers before submission to making assurance of following our anti-plagiarism policies.
